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Catalog	name	Description	price
R-R-0330	DCL (PSMA inhibitor) (ACUPA)	DCL (PSMA inhibitor) (ACUPA) is an amino-modified amino acid and a new type of inhibitor that has a highly inhibitory effect on prostate-specific membrane antigen (PSMA). It is introduced into polypeptides through chemical synthesis, thereby changing the properties and activity of the polypeptide. ACUPA-modified amino groups have stability and water solubility, which can enhance the affinity and selectivity of peptides, thereby improving the efficacy and biological activity of peptides. It can also alter the metabolism and distribution of peptides.	price>
R-XASYS-00331	6-Shogaol,cas:555-66-8	6-Shogaol(C17H24O3,276.4) is a minor, bioactive component of ginger (Zingiber officinale Roscoe) with anti-inflammatory and anticancer properties. It is present in fresh ginger at low levels, but quantities of 6-shogaol are significantly increased in dried ginger. 6-Shogaol induces apoptosis in cancer cells through the production of reactive oxygen species and the activation of caspase.	price>
R-R-0331	NOTA-PSMA	NOTA PSMA/Cas: 1575386-67-2, macrocyclic compound PSMA, is a ligand with unique properties. PSMA is a non-essential, low-abundance membrane protein with glutamate carboxypeptidase B activity. PSMA is expressed in prostate cancer but is not expressed or has low expression in normal prostate tissue. NOTA-PSMA is a targeted imaging agent based on PSMA (prostate-specific membrane antigen) that can be used for the diagnosis and treatment of prostate cancer.	price>
R-XASYS-00332	(±)-Dunnione,cas:521-49-3	(±)-Dunnione(C15H14O3,242.3) is a naturally occurring naphthoquinone with diverse biological activities.It exhibits fungicidal activity against ten agriculturally relevant plant fungi in vitro (MICs = 5-20 mg/L) and in infected wheat and barley plants (EC50s = 2-20 mg/L).1 (±)-Dunnione also reduces the growth of T. cruzi epimastigotes (IC50 = 4.01 μM).	price>
R-R-0332	tert-Butyl-DCL (PSMA inhibitor)	Tert-butyl-DCL/CAS:1025796-31-9 is a small molecule inhibitor that targets prostate-specific membrane antigen (PSMA) for potential cancer therapy. PSMA is a cell surface glycoprotein that is highly expressed in prostate cancer cells, making it a promising target for cancer treatment. Tert-butyl-DCL is designed to specifically bind to PSMA and inhibit its activity, which may lead to the suppression of prostate cancer cell growth and proliferation. This inhibitor is currently being studied in preclinical and clinical trials to evaluate its efficacy and safety as a potential treatment for prostate cancer and other PSMA-expressing cancers.	price>
R-XASYS-00333	Sciadopitysin,cas:521-34-6	Sciadopitysin(C33H24O10,580.5) is a biflavonoid originally isolated from G. biloba and has diverse biological activities.It reduces cytotoxicity induced by amyloid-β (1-42) (Aβ42) in PC12 cells (EC50 = 9.84 μM).2 Sciadopitysin (0.1-10 μM) decreases methylglyoxal-induced insulin secretion, production of reactive oxygen species (ROS)	price>
R-R-0333	PSMA-ligand-1	PSMA-ligand-1/CAS:1610413-97-2 is a molecule that specifically binds to prostate-specific membrane antigen (PSMA). This molecule is used in diagnostic imaging techniques, such as positron emission tomography (PET) scans, to detect and locate prostate cancer lesions. Additionally, PSMA-ligand-1 conjugated to a therapeutic compound can be used in targeted therapy to deliver treatment directly to PSMA-expressing cancer cells. The development and use of PSMA-ligand-1 hold promise for improving the early detection and treatment of prostate cancer.	price>
R-XASYS-00334	Pulchinenoside B4,cas:129741-57-7	Pulchinenoside B4(C59H96O26,1221.4) is a triterpenoid glycoside that has been found in P. chinensis and has diverse biological activities.It inhibits cisplatin-induced apoptosis, increases in reactive oxygen species (ROS) production, and decreases in superoxide dismutase (SOD) and catalase activities in HEK293 cells when used at concentrations of 6 and 12 μM.	price>
R-R-0334	DCFPYL	DCFPYL/CAS: 1423758-00-2/Piflufolastat can be used to prepare DCFPYL F-18. Pyroflofolate F-18. Pyroflofolate F-18 is an 18F labeled diagnostic imaging agent. Pirflulastatin F-18 can be used for positron emission tomography (PET) targeting (PSMA).	price>
R-XASYS-00335	R162,cas:64302-87-0	R162(C17H12O3,264.3) is an inhibitor of glutamate dehydrogenase 1 (GDH1; IC50 = 23 µM). It decreases intracellular fumarate levels and increases the production of mitochondrial reactive oxygen species (ROS) in human H1299 lung and MDA-MB-231 breast cancer cells.	price>
R-R-0335	PSMA-BCH	PSMA-BCH/CAS: 1703768-73-3 also known as NOTA-PSMA, is a PSMA- NOTA-conjugated precursor. 68Ga-PSMA-BCH can be used for prostate cancer imaging. Al18F-PSMA-BCH can be used for prostate cancer imaging as a novel 18F PET radiotracer. 64Cu-PSMA-BCH is a new radiotracer for delayed PET imaging of prostate cancer. 64Cu-PSMA-BCH was PSMA specific and showed high stability in vivo with lower uptake in liver than 64Cu-PSMA-617. Biodistribution in mice and PCa patients showed similar profile compared with other PSMA ligands and it was safe with moderate effective dosimetry.	price>
R-XASYS-00336	Methylprotodioscin,cas:54522-52-0	Methylprotodioscin(C52H86O22,1063.2) is a steroidal saponin that has been found in A. cochinchinensis and has diverse biological activities.It suppresses mucin 5AC (MUC5AC) production induced by EGF or phorbol 12-myristate 13-acetate (PMA) in H292 cells when used at a concentration of 1 µM.1 Methylprotodioscin inhibits the proliferation of HeLa cervical cancer cells.	price>
R-R-0336	PSMA I&F	PSMA I&F is crucial for the management of prostate cancer patients as it facilitates early detection of recurrent or metastatic diseases and allows for tailored treatment methods based on individual reactions over time.	price>
R-XASYS-00337	Ginsenoside Rf,cas:52286-58-5	Ginsenoside Rf(C42H72O14,801.0) is a steroid glycoside found in plants of the genus Panax that has diverse biological activities.It inhibits production of IL-1β, IL-6, TNF-α, NO, and reactive oxygen species (ROS) in human HT-29 intestinal epithelial cells and RAW 264.7 mouse macrophages in a dose-dependent manner. Ginsenoside Rf inhibits N-type calcium channels in rat sensory neurons (IC50 = 40μM).	price>
R-R-0337	DUPA(OtBu)-OH	DUPA(OtBu)-OH/CAS:1026987-94-9 is a DUPA precursor. DUPA is used as the targeting moiety to actively deliver Docetaxel (DTX) for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer. PSMA has a high affinity for DUPA(Ki = 8 nM).	price>
R-XASYS-00338	2,3,5,4-Tetrahydroxyl-diphenylethylene 2-O-β-D-Glucoside,cas:82373-94-2	2,3,5,4-Tetrahydroxyl-diphenylethylene 2-O-β-D-glucoside (TSG)(C20H22O9,406.4) is a stilbene glucoside that has been found in P. multiflorum and has diverse biological activities.It scavenges DPPH radicals in a cell-free assay (IC50 = 40 µM).	price>
R-R-0338	Vipivotide tetraxetan Linker	Vipivotide tetraxetan Linker/CAS:1703768-74-4 is a useful peptide linker for synthesis of Vipivotide tetraxetan (PSMA-617). Vipivotide tetraxetan (PSMA-617) is a ligand used to synthesize 177Lu-PSMA-617, which is a radioactive molecule for the treatment of prostate cancer.	price>
R-XASYS-00339	Arecaidine propargyl ester (hydrobromide),cas:116511-28-5	Arecaidine propargyl ester(C10H13NO2•HBr,260.1) is an agonist of M2 muscarinic acetylcholine receptors (mAChRs).It selectively binds to M2 over M1, M3, M4, and M5 mAChRs in CHO cells expressing the human receptors (Kis = 0.0871, 1.23, 0.851, 0.977, and 0.933 µM, respectively).	price>
R-R-0339	DCL-PEG3-N3	DCL-PEG3-N3 refers to a specific molecule that is a derivative of a PSMA-targeting compound.Given the specific nature of this compound, it likely represents a targeted approach to prostate cancer treatment, potentially involving conjugation with other molecules for imaging or therapeutic purposes.	price>
R-XASYS-00340	CAY10735,cas:2251753-58-7	CAY10735(C44H60FN3O4,714.0) is an anticancer compound.It inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.674-11.56μM). CAY10735 inhibits migration of and the epithelial-to-mesenchymal transition (EMT) in A375 and B16/F10 melanoma cells in vitro in a concentration-dependent manner.	price>

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