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R-R-0320 cyclic Arg(Pbf)-Gly-Asp(Ot-Bu)-D-Tyr(Ot-Bu)-Lys(NH2) Cyclic Arg(Pbf)-Gly-Asp(Ot-Bu)-D-Tyr(Ot-Bu)-Lys(NH2)/CAS: 903518-34-3 refers to a specific sequence of amino acids forming a cyclic peptide. Arg-Gly-Asp-Tyr-Lys in this peptide is of particular interest in the field of peptide chemistry and molecular biology, as it is a component of the RGD (Arg-Gly-Asp) motif, which has high affinity for integrin receptors and is involved in cell adhesion, migration, and other cellular processes. Peptides containing the RGD motif have been extensively studied for their potential applications in targeted drug delivery, molecular imaging, and as therapeutics for conditions such as cancer and angiogenesis-related diseases. price>
R-XASYS-00321 Lipofermata,cas:297180-15-5 Lipofermata(C15H10BrN3OS,360.2) is an inhibitor of fatty acid transport (IC50 = 4.84 μM in Caco-2 cells).It inhibits uptake of long- and very long-chain, but not medium-chain, fatty acids in mmC2C12, rnINS-1E, Caco-2, and HepG2 cells (IC50s = 3-6 μM).Lipofermata inhibits induction of BiP and CHOP, apoptosis, and lipid droplet accumulation. price>
R-R-0321 Cyclo(-RGDfK) Cyclo(-RGDfK)/cas:161552-03-0 is a cyclic peptide sequence containing the RGD motif. Cyclo(-RGDfK) and related cyclic peptides containing the RGD motif have been extensively studied for their potential applications in cancer targeting, tumor imaging, and angiogenesis inhibition. These peptides have shown promise in targeted drug delivery systems, molecular imaging, and as therapeutic agents due to their high affinity for integrin receptors, which are often overexpressed in cancer cells and angiogenic blood vessels. price>
R-XASYS-00322 Sesamolin,cas:526-07-8 Sesamolin(C20H18O7,370.4) is a lignin found in S. indicum with diverse biological activities. It reduces lipid peroxidation in rat liver and kidneys in vivo but has no effect on lipid peroxidation activity of rat liver microsomes in vitro. price>
R-R-0322 Cyclic(RGDyK) Cyclo(RGDyK)/CAS: 250612-42-1 is a selective and potent αVβ3 integrin inhibitor with IC50 value of 20 nM [1]. The αVβ3 integrin, expressed on various malignant human tumors and on endothelial cells, plays an important role in tumor-induced angiogenesis and tumor metastasis. Therefore, αVβ3 integrin is a potential therapeutic target for tumor disease. Inhibition of αVβ3 integrin by αVβ3 antagonists not only blocked blood vessel formation but further led to tumor regression. price>
R-XASYS-00323 Cinnabarinic Acid,cas:606-59-7 Cinnabarinic acid(C14H8N2O6,300.3) is an agonist of metabotropic glutamate receptor 4 (mGluR4) and active metabolite of 3-hydroxyanthranilic acid.It is formed via two-step oxidation of 3-hydroxyanthranilic acid. price>
R-R-0323 Azido cyclic(RGDyK) Azido cyclic(RGDyK) refers to a cyclic peptide sequence containing the RGD motif with an azido functional group attached to it. The addition of the azido group to the cyclic(RGDyK) peptide expands its potential utility in applications such as bioconjugation, molecular imaging, and targeted drug delivery, allowing for precise and selective modifications and conjugations to other molecules or surfaces through bioorthogonal chemistry. price>
R-XASYS-00324 trans-Zeatin,cas:1637-39-4 trans-Zeatin(C10H13N5O,219.2) is a cytokinin plant growth regulator with antioxidant and neuroprotective activities.It binds to the cytokinin receptor Arabidopsis histidine kinase 3 (AHK3) with a KD value of 1.3 nM.trans-Zeatin increases chlorophyll levels in etiolated Cucumus sativus cotyledons in a concentration-dependent manner. price>
R-R-0324 Cyclo(-RGDfK) TFA Cyclo(RGDyK) trifluoroacetate/Cyclo(-RGDfK) TFA/CAS: 500577-51-5/Cyclo(RGDyK) trifluoroacetate refers to a cyclic peptide sequence containing the RGD motif, which has been synthesized in the form of its trifluoroacetate salt. price>
R-XASYS-00325 Tenuigenin,cas:2469-34-3 Tenuigenin(C30H45ClO6,537.1) is a triterpenoid sapogenin that has been found in P. tenuifolia and has diverse biological activities, including antioxidant, anti-inflammatory, and neuroprotective properties.It inhibits IL-1βand reactive oxygen species (ROS) production from LPS-induced mouse BV2 microglia at a concentration of 4μM price>
R-R-0325 cyclic Arg(Pbf)-Gly-Asp(Ot-Bu)-D-Phe-Lys(NH2) Heterocyclic organic compound chelating agent cyclic Arg(Pbf)-Gly-Asp(Ot_Bu)-D-Phe-Lys(NH2)CAS:226559-04-2, RGD sequence peptide has a wide range of biological activities and refers to the three amino acids consisting of Arg-Gly-Asp. Sequence peptides are divided into linear peptides and cyclic peptides. price>
R-XASYS-00326 Atractylenolide II,cas:73069-14-4 Atractylenolide II(C15H20O2,232.3) is a sesquiterpene that has been found in D. metel and has diverse biological activities.It inhibits proliferation of, as well as halts the cell cycle at the G2/M phase and induces apoptosis in, DU145 and LNCaP prostate cancer cells when used at concentrations of 50 and 100 µM. price>
R-R-0326 Azido-ApoPep-1 Azido-ApoPep-1 refers to a modified version of a peptide called ApoPep-1 that has been functionalized with an azido group (-N3). The use of azido-ApoPep-1 in research and possibly diagnostics allows for the labeling of apoptotic cells in a highly specific manner and can be helpful to visualize and quantify cell death in diseases like cancer or during therapeutic interventions. price>
R-XASYS-00327 CFTR Inhibitor-172,cas:307510-92-5 The cystic fibrosis (CF) gene encodes a cAMP-regulated chloride channel, the CF transmembrane conductance regulator (CFTR).CFTR inhibitor-172(C18H10F3NO3S2,409.4) is a thiazolidinone that selectively blocks the CFTR channel (Ki = 300 nM) in a voltage-independent manner. price>
R-R-0327 Azido-TAT Azido-TAT likely refers to a molecule with an azide group that is linked to the TAT peptide. The TAT peptide is a short peptide derived from the HIV-1 transactivator of transcription (TAT) protein, and it is known for its ability to translocate across cell membranes. This modification could be useful for applications in drug delivery, targeted imaging, or other biological studies. price>
R-XASYS-00328 Ferrostatin-1,cas:347174-05-4 Ferrostatin-1(C15H22N2O2,262.4) is a ferroptosis inhibitor.It inhibits cell death induced by the ferroptosis inducers erastin (EC50 = 60 nM) and RSL3, but not by hydrogen peroxide, rotenone, or staurosporine, in HT-1080 cells when used at a concentration of 0.5 μM. price>
R-R-0328 PSMA-617 PSMA-617/Vipivotide tetraxetan/CAS: 1702967-37-0 is a radiolabeled monoclonal antibody that binds to the tumor antigen prostate specific membrane antigen (PSMA). It has been shown to be an effective treatment for prostate cancer, with clinical studies showing a significant decrease in tumor volume and size. This drug also had a high uptake rate of urea nitrogen into the tumour xenografts, which is indicative of its effectiveness. PSMA-617 is also useful as a diagnostic tool, as it can be used to diagnose solid tumours such as breast cancer and lung cancer. The biological properties of this drug are still unclear, but it has been shown to have anti-tumor effects when used in combination with radiation therapy. price>
R-XASYS-00329 Levistolide A,cas:88182-33-6 Levistolide A(C24H28O4,380.5) is a phthalide that has been found in Angelica tenuissima and has diverse biological activities.It inhibits histamine release induced by phorbol 12-myristate 13-acetate (TPA) and A23187 from HMC-1 human mast cell leukemia cells when used at a concentration of 10 µM. price>
R-R-0329 HYNIC-PSMA HYNIC-PSMA is a ligand for molecular imaging of tumors. Hynic-psma consists of two components: HYNIC (6-hydrazinonicotinamide) and PSMA (Prostate-Specific Membrane Antigen). HYNIC is a compound used to attach radioactive isotopes to targeted molecules, such as 188Re-HYNIC-PSMA. PSMA is a membrane antigen that is specifically expressed on the surface of prostate cancer cells. HYNIC-PSMA can be used in prostate cancer research. price>
R-XASYS-00330 LY345899,cas:10538-99-5 LY345899(C20H21N7O7,471.4) is an inhibitor of methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) and MTHFD2 (IC50s = 96 and 663 nM, respectively).It decreases the NADPH-to-NADP+ (NADPH/NADP+) and reduced glutathione-to-oxidized glutathione (GSH/GSSG) ratios and increases the production of reactive oxygen species (ROS) in HCT116, SW620, and LoVo colorectal cancer cells when used at a concentration of 10 µM. price>