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Catalog | name | Description | price |
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R-R-0300 | FAPI-2 | FAPI-2/Fibroblast-activation-protein inhibitor-2/CAS .2370952-98-8 is a small molecule compound designed to target fibroblast activation protein (FAP), an enzyme that is overexpressed in the tumor microenvironment of various cancers, including pancreatic, colorectal, lung, and breast cancer. | price> |
R-XASYS-00301 | GLX-351322,cas:835598-94-2 | GLX-351322(C21H25N3O5S,431.5) is an inhibitor of NADPH oxidase 4 (NOX4; IC50 = 5 µM).It is selective for NOX4 over NOX2 (IC50 = 40 µM). GLX-351322 (10 µM) reduces glucose-induced production of reactive oxygen species (ROS) and cytotoxicity in isolated human pancreatic islets. | price> |
R-R-0301 | Fmoc-FAPI-4 | Fmoc-FAPI-4 is a specific fibroblast activation protein inhibitor (FAPI) compound that is a member of the FAPI family of molecules. Fmoc-FAPI-4, like other FAPI compounds, is intended to selectively accumulate in FAP-positive tumors and disrupt the functions of cancer-associated fibroblasts (CAFs) in the tumor microenvironment. By inhibiting FAP activity, these compounds aim to potentially slow down tumor growth, enhance the efficacy of other cancer treatments, and modulate the tumor microenvironment. | price> |
R-XASYS-00302 | Talaporfin (sodium salt),cas:220201-34-3 | Talaporfin(C38H37N5O9•4Na,799.7) is a photosensitizer.It induces apoptosis, DNA double-strand breaks (DSBs), and the production of reactive oxygen species (ROS) in TE-11R 5-fluorouracil-resistant esophageal squamous cell carcinoma (ESCC) cells when used at a concentration of 30 µg/ml in combination with radiation. | price> |
R-R-0302 | SH-FAPI-4 | SH-FAPI-4 is a specific fibroblast activation protein inhibitor (FAPI) compound that belongs to the FAPI family of molecules. SH-FAPI-4 is expected to selectively accumulate in FAP-positive tumors and disrupt the functions of cancer-associated fibroblasts (CAFs) within the tumor microenvironment. By inhibiting FAP activity, this compound aims to potentially slow tumor growth, enhance the efficacy of other cancer treatments, and modulate the tumor microenvironment. | price> |
R-XASYS-00303 | CAY10730,cas:2206677-06-5 | CAY10730 is a turn-on fluorescent probe for the detection of nitroreductase activity, a marker of hypoxia.In the presence of nitroreductase, CAY10730 is transformed into a highly fluorescent molecule that displays excitation/emission maxima of 454/520 nm, respectively. | price> |
R-R-0303 | FAPI | FAPI stands for fibroblast activation protein inhibitor. FAPI compounds are a class of small molecule inhibitors designed to target and inhibit fibroblast activation protein (FAP). FAP is an enzyme that is overexpressed in the tumor microenvironment of various cancers, including pancreatic, colorectal, lung, and breast cancer. | price> |
R-XASYS-00304 | Fuziline,cas:80665-72-1 | Fuziline is a diterpene alkaloid that has been found in A. lateralis and has cardioprotective activity.It reduces sodium pentobarbital-induced cell death in primary neonatal rat cardiomyocytes when used at concentrations ranging from 0.1 to 10 µM. | price> |
R-R-0304 | UAMC1110 | UAMC-1110, also known as SP-13786, is a novel potent and selective inhibitor of fibroblast activation protein (fap), displaying low nanomolar inhibitory potency and high selectivity against the related dipeptidyl peptidases (dpps) dppiv, dpp9, dppii, and prolyl oligopeptidase (prep). | price> |
R-XASYS-00305 | Necrox-5 (methanesulfonate),cas:1383718-29-3 | Necrox-5(C25H31N3O3S•2CH4O3S,1383718-29-3) is a cell permeable inhibitor of necrosis that also demonstrates strong mitochondrial reactive oxygen species and ONOO- scavenging activity.It predominantly localizes in mitochondria, selectively blocking oxidative stress-induced necrotic cell death (0.1 μM necrox-5 inhibits ~50% cell death in H9C2 cells exposed to 400 μM t-BHP) | price> |
R-R-0305 | NH2-UAMC1110 | NH2-UAMC1110 is a UAMC1110 derivative that can be used in the synthesis of FAPI-QS. FAPI-QS is a chelating agent that can be used to manufacture high tumor selectivity and high dose radiotracers for the diagnosis and treatment of tumors. | price> |
R-XASYS-00306 | Terrecyclic Acid,cas:83058-94-0 | Terrecyclic acid is a sesquiterpene originally isolated from A. terreus with antibiotic and anticancer activity.It is active against S. aureus, B. subtilis, and M. roseus (MICs = 25, 50, and 25 μg/ml, respectively). Terrecyclic acid induces a heat shock response, increases levels of reactive oxygen species (ROS), and inhibits NF-κB activity and cell growth in 3T3-Y9-B12 cells. | price> |
R-R-0306 | DOTA-Octreotide | DOTA-Octreotide, also known as DOTA-TOC, is a radiolabeled peptide-based radiopharmaceutical used in diagnostic imaging and targeted therapy for certain neuroendocrine tumors (NETs). | price> |
R-XASYS-00307 | Daunorubicin (hydrochloride),cas:23541-50-6 | Daunorubicin is an antitumor antibiotic.1 At 0.2-1μM, daunorubicin induces apoptosis in mature monocytic U937 and myelocytic HL-60 acute myeloid leukemia (AML) cells. However, immature AML cells (CD 34+-KG1a, -KG1, or -HEL cells) appear resistant to apoptosis at similar concentrations. | price> |
R-R-0307 | Hynic-TOC | Hynic-TOC/Hynic-Toc Trifluoroacetate/Cas257943-19-4 from ruixi. Hynic-TOC, also known as 6-hydrazinonicotinyl-Tyr3-octreotide, is a radiolabeled peptide-based radiopharmaceutical used in nuclear medicine imaging. | price> |
R-XASYS-00308 | Procyanidin B1,cas:20315-25-7 | Procyanidin B1(C30H26O12,578.5) is a polyphenol flavonoid existing as a dimer of (+)-catechin and (−)-epicatechin. It inhibits hepatitis C virus RNA replication (EC50 = 72 µM), while (+)-catechin and (−)-epicatechin do not, up to concentrations of 200 µM.1 Procyanidin B1 (10 µg/ml) | price> |
R-R-0308 | Pentixafor CAS: 1341207-62-2 | Pentixafor is a medicinal compound that has been developed as an anticancer agent. This compound is an analog of the CXCR4 receptor inhibitor, which is found in human urine and Chinese medicinal herbs. Pentixafor works by inhibiting kinases that are involved in cancer cell growth and survival, leading to apoptosis or programmed cell death. It specifically targets tumor cells and prevents them from spreading to other parts of the body. Pentixafor has shown promising results in preclinical studies for the treatment of various types of cancer, including breast, prostate, and lung cancer. Its ability to selectively target cancer cells makes it a potential breakthrough in cancer treatment research. | price> |
R-XASYS-00309 | Sitamaquine (tosylate),cas:1019640-33-5 | Sitamaquine(C21H33N3O•C7H8O3S,515.7) is an antileishmanial agent.It is active against L. donovani, L. infantum, L. mexicana, L. braziliensis, and L. tropica.It inhibits mitochondrial complex II, also known as succinate dehydrogenase (SDH), in a cell-free assay when used at concentrations ranging from 10 to 200 µM. | price> |
R-R-0309 | NOTA-NFB | NOTA-NFB is a very useful peptide labeling reagent that can label proteins or other biomolecules with groups with specific functions. By using NOTA-NFB, it is easier to study the function and behavior of biomolecules, as well as their interactions with other molecules. | price> |
R-XASYS-00310 | Hypocrellin B,cas:123940-54-5 | Hypocrellin B(C30H24O9,528.5) is a fungal metabolite that has been found in H. bambuase and has anticancer and antibacterial activities.It acts as a sonosensitizer, decreasing the viability of MDA-MB-231 breast cancer cells and inducing apoptosis in the presence of ultrasound exposure, effects that can be inhibited by the caspase inhibitor z-VAD-FMK. | price> |