Home > Keywords >
Catalog | name | Description | price |
---|---|---|---|
R-C-5553 | Amino-Gly-Gly-DSPE | Amino-Gly-Gly-DSPE is a lipid molecule that consists of a glycerol backbone linked to a long hydrophobic acyl chain and an amino acid dipeptide, glycine-glycine, attached to the glycerol through an amide bond.The long acyl chains of DSPE provide hydrophobic properties, making it suitable for the self-assembly of lipids into lipid bilayers. | price> |
R-M2-9571 | NaYF4: 5% Tm3+,50% Er3+@NaYF4 Upconversion nanoparticles,EX:1208nm | NaYF4: 5% Tm3+,50% Er3+@NaYF4 Upconversion nanoparticles is a new type of Tm3+ sensitized lanthanide nanocrystals in the NIR-II window for in vivo optical information storage and decoding.Taking advantage of the tunable fluorescence lifetimes, the optical multiplexed encoding capacity is enhanced accordingly.Micro-devices with QR codes featuring the NIR-II fluorescence-lifetime multiplexed encoding were implanted into mice and were successfully decoded through time-gated fluorescence imaging technology. | price> |
R-M-7041 | AZDye 488 Acid | AZDye™ 488 is a water-soluble, highly photostable dye with a very high fluorescence quantum yield. AZDye™ 488 is green-emitting dye with excitation ideally suited for the 488 nm line. Its fluorescence is pH independent from pH 4 to pH 10. | price> |
R-M2-9572 | Ac-RVRRCK-PEG5K-SH | Ac-RVRRCK-PEG5K-SH/Ac-RVRRCK-PEG5K-thiol is a peptide modified PEG compound.The PEGylation can enhance solubility and stability in circulation, while the RVRRCK sequence might facilitate cellular uptake.The free thiol (-SH) allows for conjugation to other molecules, like drugs, imaging agents, or nanomaterials, through thiol-maleimide chemistry, among other approaches.The peptide may be used in the development of synthetic constructs that require targeted delivery or penetration into cells.If incorporated into liposome formulations, it could be used to examine the effects of cell-penetrating peptides on liposome stability and encapsulation efficiency. | price> |
R-M-7042 | AZDye 488 Maleimide | AZDye™ 488 is a green-fluorescent, water-soluble dye with pH insensitive emission from pH 4 to pH 10. This dye is ideally suited to the 488 nm laser line. AZDye 488 is one of the brightest dyes commercially available with fluorescence quantum yield close to 100%. AZDye™ 488 Maleimide dye is structurally identical to Alexa Fluor® 488 C5 Maleimide dye. Its absorption/emission spectra is a perfect match to spectra of many other fluorescent dyes based on sulfonated rhodamine 110 core, including CF®488 Dye, DyLight® 488 and Alexa Fluor® 488. | price> |
R-M2-9573 | DOTA-PEG8-NHCO-MeTz | DOTA-PEG8-NHCO-Methyltetrazine represents a multifunctional chemical entity that harnesses the properties of each component for potential applications in medical imaging, targeted delivery, and therapeutic interventions. The DOTA portion can be used to chelate radioactive metals, making the whole compound suitable for radiolabeling applications in medical imaging (like PET scans).The PEG component can improve the solubility and circulation time of the compound in vivo, while the methyltetrazine can be engaged in bioorthogonal reactions for targeted delivery of drugs or imaging agents.The structure can be tailored further to create conjugates with therapeutic agents, providing targeted treatment options in oncology or other fields. | price> |
R-M-7043 | AZDye 488 Cadaverine | AZDye™ 488 Cadaverine is a carbonyl reactive building block used to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be employed as a polar tracer and as a reactive dye for labeling proteins via a carboxylic acid moiety. | price> |
R-M2-9574 | NH2-PEG2000-MG1(C-HHSSSAR-C) | NH2-PEG2000-MG1(C-HHSSSAR-C)/NH2-PEG2000-MG1 is a multifunctional compound designed for applications in drug delivery or targeted therapeutics. The PEG component enhances biocompatibility, while the amino group allows for conjugation, and the peptide sequence could provide specificity in targeting. | price> |
R-M-7044 | AZDye 488 DBCO | AZDye™ 488 DBCO reacts with azides via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, AZDye™ 488 DBCO is an ideal alternative to copper requiring fluorescent alkynes.The brightness and photostability of AZDye™ 488 is best suited to direct imaging of low-abundance targets. | price> |
R-M2-9575 | Arginine-PEG1K-N3 | Arginine-PEG1K-N3 is a multifunctional compound that potentially serves important roles in drug delivery and targeted therapeutics. The combination of arginine for cellular uptake, PEG for solubility and stability, and the azide group for conjugation makes it a versatile tool in medicinal chemistry and bioconjugation strategies. | price> |
R-M-7045 | AZDye 488 Azide | AZDye™ 488 Azide is a bright, green-fluorescent, azide-activated probe that reacts with terminal alkynes via a copper-catalyzed click reaction (CuAAC). It also reacts with strained cyclooctynes via a copper-free click chemistry reaction to form a stable triazole and does not require a Cu-catalyst or elevated temperatures.The brightness and photostability of AZDye™ 488 dyes are best suited to direct imaging of low-abundance targets. | price> |
R-M2-9576 | SH-PEG2K-L-Arginine | SH-PEG2K-L-Arginine is a versatile compound with significant potential in drug delivery and bioconjugation research. Its structure, featuring a thiol, a polyethylene glycol moiety, and L-arginine, provides a platform for various chemical modifications and applications, enhancing the efficacy and targeting capabilities of therapeutic agents. | price> |
R-M-7046 | AZDye 488 Picolyl Azide | AZDye™ 488 Picolyl Azide is an advanced fluorescent probe that incorporates a copper-chelating motif to raise the effective concentration of Cu(I) at the reaction site. The introduction of a picolyl moiety into an azide probe leads to a substantial increase in the sensitivity of alkyne detection. This is of special value for the detection of low abundance targets or where significant increase in signal intensity is desired. | price> |
R-M2-9577 | Biotin-HDCA | Biotin-HDCA,Biotin-Hyodeoxycholic Acid might be marketed as a dietary supplement aimed at improving metabolic health, supporting fat metabolism, and promoting hair and skin health.Research into bile acids, including HDCA, has grown due to their roles beyond digestion, influencing metabolic diseases, gut health, and liver function. | price> |
R-M-7047 | AZDye 488 Alkyne | AZDye™488 Alkyne is a bright, green-fluorescent, alkyne-activated probe routinely used for imaging of low abundance azide-containing biomolecules. AZDye™ 488 Alkyne reacts with azides via a copper-catalyzed click reaction (CuAAC) to form a stable triazole linker.The brightness and photostability of AZDye™ 488 is best suited to direct imaging of low-abundance targets. | price> |
R-M2-9578 | CY5-Taurodeoxycholic acid sodium hydrate | CY5-Taurodeoxycholic acid sodium hydrate/Cyanine 5-Taurodeoxycholic acid sodium hydrate/Taurodeoxycholic acid sodium hydrate,Cyanine 5 labed can be used for cellular imaging,Biliary Transport Studies,Drug Delivery,Signaling Pathways,In Vivo Studies. The CY5 fluorophore allows for visualization of cells or tissues, making it possible to study the distribution and dynamics of TDCA in various biological contexts. CY5-Taurodeoxycholic acid sodium hydrate can be used to investigate how taurodeoxycholic acid and other bile acids are transported across cellular membranes, potentially aiding in understanding enterohepatic circulation. Given the natural role of bile acids in lipid absorption, CY5-TDCA could be explored for its ability to deliver therapeutic payloads, particularly for liver and gastrointestinal diseases. Study of the role of bile acids in cellular signaling and the impact on metabolic disorders, obesity, or liver diseases. The near-infrared properties of CY5 can be beneficial for in vivo imaging, providing insights into biological processes in live subjects with minimal interference from tissue autofluorescence. | price> |
R-M-7048 | AZDye 488 Hydroxylamine | AZDye 488 Hydroxylamine (aminooxy) reacts with aldehydes and ketones to yield oximes. Oximes are superior to hydrazones with respect to hydrolytic stability. AZDye 488 Hydroxlamine often used as membrane-impermeant, aldehyde-fixable cell tracers as well as reactive dye for labeling aldehydes or ketones in polysaccharides or glycoproteins. | price> |
R-M2-9579 | CY2-Taurochenodeoxycholic Acid | CY2-Taurochenodeoxycholic Acid/Cyanine2-Taurochenodeoxycholic Acid/Taurochenodeoxycholic Acid,CY2 labed serves as a valuable tool for studying bile acid biology, metabolic processes, and cellular uptake mechanisms. The conjugation of taurochenodeoxycholic acid with a fluorescent dye like CY2 enhances the ability to visualize and understand complex interactions in biological systems. | price> |
R-M-7049 | AZDye™ 532 NHS Ester | AZDye™ 532 NHS Ester is an amine reactive, yellow-emitting dye routinely used to label proteins or antibodies through primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond.It is often used for the generation of stable signals in imaging and flow cytometry. | price> |
R-M2-9580 | CY5-Hyodeoxycholic Acid | The CY5 conjugation allows researchers to visualize the distribution and cellular uptake of hyodeoxycholic acid within cells and tissues using fluorescence microscopy or flow cytometry. The effects of hyodeoxycholic acid on metabolic processes, including lipid metabolism and bile acid signaling pathways, can be explored using this fluorescent conjugate to track movement of HDCA in biological samples. CY5-HDCA/Cyanine5-Taurochenodeoxycholic Acid/Taurochenodeoxycholic Acid,CY5 labed can be employed to understand the interactions of bile acids with gut microbiota and their impact on gastrointestinal health and disease. Due to the amphipathic nature of bile acids, CY5-HDCA might be used as a carrier for lipophilic drugs, enhancing the absorption and efficacy of therapeutic agents. Utilization of the CY5 label in vivo could provide insights into the pharmacokinetics and dynamics of hyodeoxycholic acid in animal models, offering opportunities to study liver function, biliary excretion, and the influence of bile acids on various physiological processes. | price> |