Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde,CAS :158442-41-2
Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde
Product description
Z-IE(OtBu)AL-CHO is an inhibitor of chymotrypsin-like activity of the multicatalytic proteinase complex (MPC; 20S proteasome) in HT4 cells. It is the first inhibitor reported so far which can cause accumulation of ubiquitinylated proteins in neuronal cells. Furthermore, this compound induced massive apoptosis in murine leukaemia L1210 cells. Therefore, proteasome inhibitors may be considered as potential anti-neoplastic agents.
Appearance | N/A |
---|---|
Molecular weight | N/A |
Purity | >90% |
Solubility | N/A |
Cas | 158442-41-2 |
Synonyms | Proteasome Inhibitor I, PSI, Z-IE(OtBu)AL-CHO (PSI)1,Z-Ile-Glu(OtBu)-Ala-L-leucinal,Z-Ile-Glu(OtBu)-Ala-Leu-CHO |
Molecular Formula | C₃₂H₅₀N₄O₈ |
Storage | -20℃,protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
Document
Related Product