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Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde,CAS :158442-41-2

Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde

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R-M-1257 5mg 130.00
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Product description

Z-IE(OtBu)AL-CHO is an inhibitor of chymotrypsin-like activity of the multicatalytic proteinase complex (MPC; 20S proteasome) in HT4 cells. It is the first inhibitor reported so far which can cause accumulation of ubiquitinylated proteins in neuronal cells. Furthermore, this compound induced massive apoptosis in murine leukaemia L1210 cells. Therefore, proteasome inhibitors may be considered as potential anti-neoplastic agents.


Appearance N/A
Molecular weight N/A
Purity >90%
Solubility N/A
Cas 158442-41-2
Synonyms Proteasome Inhibitor I, PSI, Z-IE(OtBu)AL-CHO (PSI)1,Z-Ile-Glu(OtBu)-Ala-L-leucinal,Z-Ile-Glu(OtBu)-Ala-Leu-CHO
Molecular Formula C₃₂H₅₀N₄O₈
Storage -20℃,protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
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