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Xevinapant hydrochloride CAS No.1071992-57-8
Xevinapant hydrochloride CAS No.1071992-57-8
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-1742 | 20mg | 280.00 | + Add to cart |
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| R-R-1742 | 50mg | 560.00 | + Add to cart |
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Product description
Xevinapant (AT-406) hydrochloride/CAS No.1071992-57-8 is a potent and orally bioavailable Smac mimetic and an antagonist of the inhibitor of apoptosis proteins (IAPs). Xevinapant hydrochloride binds to XIAP, cIAP1, and cIAP2 proteins with Kis of 66.4, 1.9, and 5.1 nM, respectively. Xevinapant hydrochloride effectively antagonizes XIAP BIR3 protein in a cell-free functional assay, induces rapid degradation of cellular cIAP1 protein, and inhibits cancer cell growth in various human cancer cell lines. Xevinapant hydrochloride is highly effective in induction of apoptosis in xenograft tumors.
| Appearance | N/A |
|---|---|
| Molecular Weight | 598.18 |
| Purity | >90% |
| CAS | 1071992-57-8 |
| Formula | C32H44ClN5O4 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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