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Voclosporin

Voclosporin

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-R-0360 100mg 2060.00
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Product description

Voclosporin/CAS.515814-01-4/ISATX247, a structurally similar analogue of cyclosporin A, is a new type of calcineurin inhibitor. It has been modified to increase its activity by 3-4 times and exhibits a dual and synergistic mechanism. This drug works by blocking the expression of IL-2 and T cell-mediated immune response, stabilizing renal podocytes. Compared to cyclosporin, voclosporin has the advantage of having less impact on cholesterol and triglycerides and a lower risk of diabetes. In February 2021, vorcyclosporine was approved by the FDA for use in combination immunosuppressive regimens in adult patients with active, lupus nephritis.

Voclosporin

Appearance N/A
Molecular Weight 1214.65
Purity >90%
CAS 515814-01-4
Formula C63H111N11O12
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
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