TCO-PEG-Epoxides

TCO-Polyethylene glycol---Epoxides,TCO-PEG-Epoxides,Epoxides-PEG-TCO from ruixi TCO will react with tetrazines via inverse electron demand Diels-Alder cycloaddition to form a stable dihydropyridazine linkage. The extremely fast kinetics and selectivity enables the conjugation of two low abundance biopolymers in an aqueous and otherwise complex chemical environment. This bioorthogonal reaction possesses excellent selectivity and biocompatibility such that the complimentary partners can react with each other within richly functionalized biological systems, in some cases, living organisms. Thus, tetrazine-TCO ligation has found numerous applications in fluorescent imaging, drug delivery, PET and SPECT imaging, radionuclide therapy, radiochemistry or drug target identification among several others.

msds of TCO-PEG-Epoxides.pdf