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Email:sales@ruixibiotech.com
Tel.:02988811435
TAE684 (NVP-TAE684) cas:761439-42-3
TAE684 (NVP-TAE684)
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-C-1001 | 10mg | 110.00 | + Add to cart |
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| R-C-1001 | 50mg | 305.00 | + Add to cart |
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| R-C-1001 | 100mg | 535.00 | + Add to cart |
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Product description
TAE684(NVP-TAE684)is a selective inhibitor of ALK with IC50 value of 3 nM .TAE684(NVP-TAE684)is a potent ALK inhibitor and has a different selectivity with the reported ALK inhibitor crizotinib.When tested with ALCL cell lines—Karpas-299 and SU-DHL-1 expressing NPM-ALK,TAE684(NVP-TAE684)inhibited cell proliferation and cell apoptosis in dose-dependent manner.In lung cancer cell lines harboring wild-type,H694R or E1384K mutant ALKs,TAE684 showed effective inhibition on cell proliferation and phospho-Y1604 ALK expression of H694R or E1384K mutant ALK,but also to a degree higher than that of wild-type ALK.
| Appearance | N/A |
|---|---|
| Molecular Weight | N/A |
| purity | >95% |
| PDI by GPC | <1.5 |
| Solubility | N/A |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
Document
msds---TAE684 (NVP-TAE684) Related Product
RuixiBiotechCo.Ltd /KamulinBiotechco.ltd
Add: Room 20F 2002, Meiyuan Building, Yanta District, Xi’ an City, Shaanxi Province 710061 China
Tel: 02988811435
Fax: (86-29)8881-1435
Email: sales@ruixibiotech.com
Web: http://www.ruixibiotech.com
