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SC144 hydrochloride CAS No.917497-70-2
SC144 hydrochloride CAS No.917497-70-2
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-1446 | 50mg | 310.00 | + Add to cart |
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| R-R-1446 | 100mg | 520.00 | + Add to cart |
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Product description
SC144 hydrochloride/CAS No.917497-70-2 is a first-in-class, orally active gp130 (IL6-beta) inhibitor. SC144 hydrochloride binds gp130, induces gp130 phosphorylation (S782) and deglycosylation, abrogates Stat3 phosphorylation and nuclear translocation, and further inhibits the expression of downstream target genes. SC144 hydrochloride shows potent inhibition of gp130 ligand-triggered signaling. SC144 hydrochloride induces apoptosis in human ovarian cancer cells.
| Appearance | N/A |
|---|---|
| Molecular Weight | 358.76 |
| Purity | >90% |
| CAS | 917497-70-2 |
| Formula | C16H12ClFN6O |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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msds of SC144 hydrochloride CAS No.917497-70-2 Related Product
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