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(R)-CR8 trihydrochloride CAS No.1786438-30-9
(R)-CR8 trihydrochloride CAS No.1786438-30-9
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-1912 | 50mg | 430.00 | + Add to cart |
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| R-R-1912 | 100mg | 740.00 | + Add to cart |
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Product description
(R)-CR8 (CR8) trihydrochloride/CAS No.1786438-30-9, a second-generation analog of Roscovitine, is a potent CDK1/2/5/7/9 inhibitor. (R)-CR8 trihydrochloride inhibits CDK1/cyclin B (IC50=0.09 μM), CDK2/cyclin A (0.072 μM), CDK2/cyclin E (0.041 μM), CDK5/p25 (0.11 μM), CDK7/cyclin H (1.1 μM), CDK9/cyclin T (0.18 μM) and CK1δ/ε (0.4 μM). (R)-CR8 trihydrochloride induces apoptosis and has neuroprotective effect. (R)-CR8 trihydrochloride acts as a molecular glue degrader that depletes cyclin K.
| Appearance | N/A |
|---|---|
| Molecular Weight | 540.92 |
| Purity | >90% |
| CAS | 1786438-30-9 |
| Formula | C24H32Cl3N7O |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
Document
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