Quinic acid-Diazirine

Quinic acid diazirine is a photo crosslinked natural product probe constructed by directionally coupling the aryl bis (aziridine) photosensitive group to the quinic acid core. It retains the core biological activities of quinic acid, such as antioxidant and anti-inflammatory, while relying on the photo covalent capture properties of bis (aziridine) to achieve precise locking of weak interactions and instantaneous binding to target proteins in living cells. It is a core tool molecule in the field of chemical biology research of cyclic polyhydroxycarboxylic acid natural products.

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