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PLGA-SS-PEG-MAL

Poly(L-lactide-co-glycolide)-S-S-Polyethylene glycol-Maleimide

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-PL1034 100mg 450.00
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R-PL1034 200mg 700.00
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R-PL1034 500mg 1000.00
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  •     PLGA Molecular Weight    
  •   
  •     MW of PEG     
  •   
  •     LA:GA    
  •   

Product description

PLGA-SS-PEG-MAL,Poly(L-lactide-co-glycolide)-S-S-Polyethylene glycol-Maleimide is a biodegradable functional amphiphilic block copolymer which hydrophilicblock PEG and hydrophobic block PLGA are linked by disulfide bond,, it canself-assemble into polymeric micelles, Maleimide on the micelle surface canconjugate with peptides, antibodies, proteins and others which contain Thiolgroups on the surface. when the micelle encounters DTT, the disulfide bondbreaks and accelerates the release of the drug.

PLGA-SS-PEG-MAL

Appearance Off-white/brown solid or viscous liquid depends on molecular weight
MW of PEG 750,1000,2000,3400,5000,10000 Dalton
MW of PLGA As your request
LA:GA 75:25, 70:30, 50:50
PDI by GPC <1.3
Substitution by NMR MAL>90%
Reactive group Thiol
Solubility Dichloromethane,Chloroform,DMF,DMSO
Storage -20℃
Transportation 4-25℃ temperature for up to 2 weeks
Stability 12 months
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