PLGA-SS-PEG-MAL
Poly(L-lactide-co-glycolide)-S-S-Polyethylene glycol-Maleimide
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
---|---|---|---|---|
R-PL1034 | 100mg | 450.00 | + Add to cart |
|
R-PL1034 | 200mg | 700.00 | + Add to cart |
|
R-PL1034 | 500mg | 1000.00 | + Add to cart |
|
|
Product description
PLGA-SS-PEG-MAL,Poly(L-lactide-co-glycolide)-S-S-Polyethylene glycol-Maleimide is a biodegradable functional amphiphilic block copolymer which hydrophilicblock PEG and hydrophobic block PLGA are linked by disulfide bond,, it canself-assemble into polymeric micelles, Maleimide on the micelle surface canconjugate with peptides, antibodies, proteins and others which contain Thiolgroups on the surface. when the micelle encounters DTT, the disulfide bondbreaks and accelerates the release of the drug.
Appearance | Off-white/brown solid or viscous liquid depends on molecular weight |
---|---|
MW of PEG | 750,1000,2000,3400,5000,10000 Dalton |
MW of PLGA | As your request |
LA:GA | 75:25, 70:30, 50:50 |
PDI by GPC | <1.3 |
Substitution by NMR | MAL>90% |
Reactive group | Thiol |
Solubility | Dichloromethane,Chloroform,DMF,DMSO |
Storage | -20℃ |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 12 months |
Document
Related Product