PF-04217903 cas:956905-27-4
PF-04217903
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-C-1006 | 10mg | 115.00 | + Add to cart |
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| R-C-1006 | 50mg | 350.00 | + Add to cart |
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| R-C-1006 | 100mg | 620.00 | + Add to cart |
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Product description
PF-04217903(PF-4217903)is a novel ATP-competitive small molecule inhibitor of c-Met kinases with the IC50 values from 3.1 nM to 142 nM.PF-04217903(PF-4217903) demonstrated>1000 fold selectivity for c-Met compared with>150 kinases, making it one of the most selective c-Met inhibitors described to date.PF-04217903(PF-4217903)inhibited tumor cell proliferation,survival,migration/invasion in MET amplified cell lines in vitro,and demonstrated marked antitumor activity in tumor models harboring either MET gene amplification or a HGF/c-Met autocrine loop at well-tolerated dose levels in vivo.
| Appearance | N/A |
|---|---|
| Molecular Weight | N/A |
| purity | >95% |
| PDI by GPC | <1.5 |
| Solubility | N/A |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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RuixiBiotechCo.Ltd /KamulinBiotechco.ltd
Add: Room 20F 2002, Meiyuan Building, Yanta District, Xi’ an City, Shaanxi Province 710061 China
Tel: 02988811435
Fax: (86-29)8881-1435
Email: sales@ruixibiotech.com
Web: http://www.ruixibiotech.com


