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PF-04217903 cas:956905-27-4

PF-04217903

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-C-1006 10mg 115.00
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R-C-1006 50mg 350.00
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R-C-1006 100mg 620.00
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Product description

PF-04217903(PF-4217903)is a novel ATP-competitive small molecule inhibitor of c-Met kinases with the IC50 values from 3.1 nM to 142 nM.PF-04217903(PF-4217903) demonstrated>1000 fold selectivity for c-Met compared with>150 kinases, making it one of the most selective c-Met inhibitors described to date.PF-04217903(PF-4217903)inhibited tumor cell proliferation,survival,migration/invasion in MET amplified cell lines in vitro,and demonstrated marked antitumor activity in tumor models harboring either MET gene amplification or a HGF/c-Met autocrine loop at well-tolerated dose levels in vivo.

PF-04217903    cas:956905-27-4

Appearance N/A
Molecular Weight N/A
purity >95%
PDI by GPC <1.5
Solubility N/A
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
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