PF-02341066 cas:877399-52-5
PF-02341066
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-C-523 | 200mg | 113.00 | + Add to cart |
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R-C-523 | 500MG | 176.00 | + Add to cart |
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R-C-523 | 1g | 320.00 | + Add to cart |
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Product description
Crizotinib(PF-02341066)is an orally bioavailable,ATP-competitive ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively.Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays,respectively.Crizotinib is also a ROS1 inhibitor.Crizotinib has effective tumor growth inhibition.
Appearance | N/A |
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Molecular Weight | N/A |
Purity | >95% |
PDI by GPC | <1.5 |
Solubility | DMSO |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
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