Obatoclax mesylate cas:803712-79-0

Obatoclax Mesylate is the mesylate salt of obatoclax,a synthetic small-molecule inhibitor of the bcl-2 family of proteins with potential pro-apoptotic and antineoplastic activities.Obatoclax binds to members of the Bcl-2 protein family,preventing the binding of these anti-apoptotic proteins to the pro-apoptotic proteins Bax and Bak and so promoting the activation of the apoptotic pathway in Bcl-2-overexpressing cells.The Bcl-2 family of proteins(bcl-2,bcl-xl, bcl-w,and Mcl-1)are overexpressed in a wide variety of cancers,including those of the lymphatic system,breast,lung,prostate,and colon.

msds---Obatoclax mesylate