NHS-SS-Biotin,CAS#: 142439-92-7

CAS#:142439-92-7,Biotin disulfide-N-hydroxysuccinimide ester.Succinimidyl-2-(biotinamido)-ethyl-1,3-dithiopropionate.NHS-SS-Biotin is an amine-reactive biotinylation reagent that contains a reducible disulfide. NHS-SS-Biotin is cell membrane per-meable and has a long chain separating the biotin group from the amino-reactive NHS-ester N-Hydroxysuccinimide ester. This product is often used to purify an antibody or other protein from a biotin specific affinity resin like immobilized streptavidin without exposing your protein of interest to denaturing conditions.

Biotinylation reagent incorporating a spacer with a cleavable disulfide linkage. Typically coupled to primary amine in the pH range 6.5-8.5. Cleavage of disulfide requires reducing agent allowing mild recovery of biotinylated compound.

COA of NHS-SS-Biotin