Mastinib cas:790299-79-5

Masitinib(AB1010)is a potent,orally bioavailable,and selective inhibitor of c-Kit(IC50=200 nM for human recombinant c-Kit).It also inhibits PDGFRα/β(IC50s=540/800 nM),Lyn(IC50= 510 nM for LynB),Lck,and,to a lesser extent,FGFR3 and FAK.Masitinib (AB1010) has anti-proliferative,pro-apoptotic activity and low toxicity.

msds ---Mastinib