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Lometrexol hydrate CAS No.1435784-14-7
Lometrexol hydrate CAS No.1435784-14-7
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-1921 | 1mg | 260.00 | + Add to cart |
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| R-R-1921 | 2mg | 420.00 | + Add to cart |
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Product description
Lometrexol (DDATHF) hydrate/CAS No.1435784-14-7, an antipurine antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol hydrate can further inhibit de novo purine synthesis, causing abnormal cell proliferation and apoptosis, even cell cycle arrest. Lometrexol hydrate has anticancer activity. Lometrexol hydrate also is a potent human Serine hydroxymethyltransferase1/2 (hSHMT1/2) inhibitor.
| Appearance | N/A |
|---|---|
| Molecular Weight | 461.47 |
| Purity | >90% |
| CAS | 1435784-14-7 |
| Formula | C21H27N5O7 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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