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L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome NBD lipid (headgroup)-DBCO
L-a-phosphatidylcholine:Cholesterol:1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-dibenzocyclooctyl(69:30:1molar ratio)-Neutral Fluoroliposome NBD lipid (headgroup)-DBCO
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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| R-Mcs-260 | 1EA | inquiry | ||
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Product description
L-alpha-PC:Chol:DOPE-N-DBCO(69:30:1molar ratio)-Neutral Fluoroliposome NBD lipid (headgroup)-DBCO can effectively encapsulate both hydrophilic and hydrophobic drugs, allowing for targeted delivery. The stability provided by cholesterol and the fusogenic properties of DOPE enhance drug efficacy and uptake in target cells.
The NBD label allows for easy tracking of the liposomes in live cells or animal models, making it ideal for studies in drug distribution, cellular uptake, and pharmacokinetics.
The DBCO modification allows for selective conjugation with azide-containing molecules, enabling the attachment of targeting ligands, fluorescent tags, or therapeutic agents, making this platform versatile for personalized medicine.
These liposomes can serve as carriers for antigens in vaccine formulations, aiding in presenting the antigens to the immune system while being tracked for efficacy.
| Appearance | Freeze-dried powder |
|---|---|
| L-alpha-PC:Chol:DOPE-N-DBCO | 69:30:1molar ratio |
| NBD lipid (headgroup) | 1,2-Distearoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl) (ammonium salt) (NBD on head group) |
| NBD lipid (headgroup)-Excitation/Emission | 460/535nm |
| Liposome Size | 100 nm |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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