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JGB1741 CAS No.1256375-38-8

Catalog #	Pkg Size	Price(USD)	Quantity	Buy this product
R-R-1427	10mg	370.00	- +	+ Add to cart
R-R-1427	25mg	720.00	- +	+ Add to cart

Product description

JGB1741 (ILS-JGB-1741)/CAS No.1256375-38-8 is a potent and specific SIRT1 activity inhibitor with an IC50 of ∼15 μM. JGB1741 is a weak SIRT2 and SIRT3 inhibitor with an all IC50>100 μM. JGB1741 increases the acetylated p53 levels leading to p53-mediated apoptosis with modulation of Bax/Bcl2 ratio, cytochrome c release and PARP cleavage. JGB1741 has the potential for breast cancer research.

Appearance	N/A
Molecular Weight	440.56
Purity	>90%
CAS	1256375-38-8
Formula	C27H24N2O2S
Storage	-20℃, protected from light and moisture
Transportation	4-25℃ temperature for up to 2 weeks
Stability	1 year

Document

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