Imatinib cas:152459-95-5

Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL,v-Abl,PDGFR and c-kit kinase activity.Imatinib (STI571) works by binding close to the ATP binding site,locking it in a closed or self-inhibited conformation,therefore inhibiting the enzyme activity of the protein semicompetitively.Imatinib also is an inhibitor of SARS-CoV and MERS-CoV.

msds---Imatinib