Glucagon [19-29],Cas:64790-15-4

Glucagon [19-29] corresponds to the C-terminal fragment of glucagon, a hormone secreted in the A cells of the islets of Langherans that plays a key role in glucose metabolism and homeostasis. Glucagon [19-29] is a potent Ca2+/Mg2+-ATPase inhibitor. It inhibits secretagogue-induced insulin secretion in beta-cells (IC50<1 pM) and Ca2+/Mg2+-ATPase activity in liver plasma membranes (IC50=0.75 nM). It also contributes to the positive inotropic effect of glucagon in cardiac cells by amplifying the cytosolic Ca2+ signal.

msds of Glucagon [19-29]