Fz7-21 TFA
Fz7-21 TFA
Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
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R-M-1787 | 10mg | 495.00 | + Add to cart |
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R-M-1787 | 25mg | 800.00 | + Add to cart |
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R-M-1787 | 30mg | 1350.00 | + Add to cart |
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Product description
Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA,a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM).
Appearance | N/A |
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Molecular weight | N/A |
Purity | >90% |
Solubility | N/A |
Sequence | Ac-Leu-Pro-Ser-Asp-Asp-Leu-Glu-Phe-Trp-Cys-His-Val-Met-Tyr-NH2 |
One letter sequence | Ac-LPSDDLEFWCHVMY-NH2 |
Molecular Formula | C₈₅H₁₁₅N₁₈F₃O₂₅S₂ |
Storage | -20℃,protected from light and moisture |
Transportation | 4-25℃ temperature for up to 2 weeks |
Stability | 1 year |
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