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Fz7-21 TFA

Fz7-21 TFA

Catalog # Pkg Size Price(USD) Quantity Buy this product
R-M-1787 10mg 495.00
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R-M-1787 25mg 800.00
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R-M-1787 30mg 1350.00
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Product description

Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA,a peptide antagonist of Frizzled 7 (FZD 7) receptors, selectively binds to FZD7 CRD subclass. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 impairs Wnt/β-catenin signaling in HEK293 cells stimulated with exogenous WNT3A (IC50=100 nM) or transfected with a construct expressing WNT3A or WNT1. Fz7-21 also blocks WNT3A-mediated stabilization of β-catenin in mouse L cells (IC50=50 nM).


Appearance N/A
Molecular weight N/A
Purity >90%
Solubility N/A
Sequence Ac-Leu-Pro-Ser-Asp-Asp-Leu-Glu-Phe-Trp-Cys-His-Val-Met-Tyr-NH2
One letter sequence Ac-LPSDDLEFWCHVMY-NH2
Molecular Formula C₈₅H₁₁₅N₁₈F₃O₂₅S₂
Storage -20℃,protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
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