Folic acid modified cationic liposome encapsulation plasmid and ICG (100-200nm)

Folic acid modified cationic liposome encapsulation of plasmid and ICG (100-200nm) from ruixibio.Cationic liposomes are lipid-based nanoparticles with a positive charge due to the presence of cationic lipids. These nanoparticles are commonly used for the encapsulation and delivery of genetic material, such as plasmid DNA, to target cells for gene therapy applications.In this case, the cationic liposomes are modified with folic acid, which acts as a targeting ligand. Folic acid receptors are often overexpressed on the surface of certain cancer cells, providing a way to specifically target these cells. By modifying the liposomes with folic acid, they can enhance cellular uptake by cancer cells that express higher levels of folate receptors.The plasmid DNA within the liposomes may contain therapeutic genes or other genetic material that can be delivered to the target cells for specific applications, such as gene therapy. Meanwhile, the indocyanine green (ICG) dye serves as both a fluorescent marker and a near-infrared (NIR) imaging agent that can provide real-time monitoring and imaging of the targeted cells.

msds of Folic acid modified cationic liposome encapsulation plasmid and ICG (100-200nm)