Endotoxin Inhibitor
H-Lys-Thr-Lys-Cys-Lys-Phe-Leu-Lys-Lys-Cys-OH (Disulfide bond)
Product description
The cyclic peptide KTKCKFLKKC has ben shown to form a strong complex with lipid A, the toxic component of the endotoxin lipopolysaccharide (LPS) . It detoxifies LPS in vitro and prevents LPS-induced cytokine release and lethality in vivo. Furthermore, it shows neither antibiotic activity nor toxicity . KTKCKFLKKC bears a structural resemblance to the peptide antibiotic and endotoxin inhibitor polymyxin B. It could be of use as an adjuvant for antibiotic therapy.
Appearance | N/A |
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Molecular weight | N/A |
Purity | >90% |
Solubility | N/A |
Cas | 147396-10-9 |
Sequence | KTKCKFLKKC |
Synonyms | K-T-K-C-K-F-L-K-K-C |
Molecular Formula | C₅₅H₉₇N₁₅O₁₂S₂ |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 3 weeks |
Stability | 1 year |
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