E7050 CAS：928037-13-2

Golvatinib,also known as E7050,is an orally bioavailable dual kinase inhibitor of c-Me,(hepatocyte growth factor receptor)and VEGFR-2(vascular endothelial growth factor receptor-2)tyrosine kinases with potential antineoplastic activity.c-Met/VEGFR kinase inhibitor E7050 binds to and inhibits the activities of both c-Met and VEGFR-2,which may inhibit tumor cell growth and survival of tumor cells that overexpress these receptor tyrosine kinases.c-Met and VEGFR-2 are upregulated in a variety of various tumor cell types and play important roles in tumor cell growth,migration and angiogenesis.

msds---E7050