DSPE-PEG-KDEL(Lys-Asp-Glu-Leu)

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-(polyethyleneglycol)-KDEL(Lys-Asp-Glu-Leu),DSPE phospholipids serve as hydrophobic anchor points embedded in the bilayer of liposomes/nanoparticles,endowing the carrier with structural stability and drug encapsulation ability. PEG chains prolong blood circulation time(2k-5k Da),reducing immune clearance and non-specific protein adsorption.Targeting sequences(Lys-Asp-Glu-Leu)specifically bind to endoplasmic reticulum retention receptors (such as GRP78/BiP).

msds----DSPE-PEG-KDEL(Lys-Asp-Glu-Leu)