DPPE-PEG-cRGD

Irgd peptide is a cyclic peptide composed of nine amino acids.It binds with AV integrins first,and then enzymolysis produces crgdk/R.it interacts with neuropilin-1 to promote the tissue permeation of drugs.It has the function of targeting tumor and tumor permeation.Integrin αVβ 3 is a kind of cell adhesion molecule highly expressed on the surface of some tumor cells and tumor neovascularization endothelial cells,but hardly expressed on the surface of normal tissues and mature blood vessels. Integrin α V β 3 can realize active targeting through mutual recognition with RGD sequences in natural ligands.

msds---DPPE-PEG-cRGD