DIR iodide(dark red fluorescence)
[1,1-dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodide]
DiR[1,1-dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodide] is a lipophilic, near infrared fluorescent cyanine dye. This dye is often used to label other lipid soluble biological structures and cell plasma membrane. The fluorescence intensity of these environmentally sensitive fluorescent dyes is very weak before they enter the cell membrane, and increases greatly when they combine with the cell membrane. It has the characteristics of high extinction coefficient, j-dependence and short lifetime of excited state. DiR [1,1-dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodide] has strong near-infrared light penetrating cells or tissues and low autofluorescence level in the near-infrared region, which makes it especially suitable for in vivo imaging or tracing experiments.
Appearance | N/A |
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Molecular weight | N/A |
Purity | >95% |
Solubility | DMSO |
Synonyms | DiR iodide |
Ex/Em | 748/780 nm |
Storage | -20℃, protected from light and moisture |
Transportation | 4-25℃ temperature for up to 3 weeks |
Stability | 1 year |
Literature website | https://pubs.acs.org/doi/abs/10.1021/acsami.0c14288 |
Literature name | Environmentally Self-Adaptative Nanocarriers Suppress Glioma Proliferation and Stemness via Codelivery of shCD163 and Doxorubicin |
Author of literature | Jie Liu, Yuxuan Zhang, Taoliang Chen,Huajian Chen, Haoqi He,Tao Jin, Jihui Wang,and Yiquan Ke |