Difluorocarboxyfluorescein NHS Ester, 5-isomer

Difluorocarboxyfluorescein NHS Ester, 5-isomer (Oregon Green™ 488 Carboxylic Acid, Succinimidyl Ester, 5-isomer equivalent) is an amine-reactive fluorinated analog of fluorescein that overcomes some of the key limitations of fluorescein, including greater photostability and a lower pKa (pKa ~ 4.7 versus 6.4 for fluorescein), making its fluorescence essentially pH insensitive in the physiological pH range. Difluorocarboxyfluorescein NHS Ester, is a preferred, routinely used fluorescent dye for labeling proteins, peptides and nucleotides.

msds of Difluorocarboxyfluorescein NHS Ester, 5-isomer