[D-Tyr6, beta-Ala11, Phe13, Nle14]-Bombesin (6-14)

[D-Tyr6, beta-Ala11, Phe13, Nle14]-Bombesin (6-14)/[D-Tyr6, ß-Ala11, Phe13, Nle14]-Bombesin (6-14) is a universal Bombesin synthetic ligand, binding to all 3 bombesin receptors. Bombesin is a 14-aa peptide originally isolated from the fire-bellied toad. It has two mammalian homologs, neuromedin and Gastrin-Releasing Peptide (GRP). It binds with high affinity to the GRP receptor, a member of the G-protein-coupled receptor family. It stimulates gastrin release from G cells, and acts in the brain to stop eating behavior. Bombesin is also a tumor marker for lung small cell carcinoma, neuroblastoma, pancreatic cancer and gastric cancer.

msds of [D-Tyr6, beta-Ala11, Phe13, Nle14]-Bombesin (6-14)