cyclo(Trp-Trp)

Cyclo(Trp-Trp)/Cyclo(L-Trp-L-Trp)/CYCLO(-TRP-TRP)/CAS 20829-55-4 is a cyclic dipeptide that has been used as a substrate for indole prenyltransferases in the synthesis of mono- and diprenylated indolines. It has antibacterial activity and inhibits growth of 41 out of 49 strains of multidrug resistant A. baumannii (MICs = 12.5-25 ug/ml) as well as B. subtilis, M. luteus, S. aureus, S. cerevisiae, A. niger, and C. albicans (MICs = 12.5-50 ug/ml). Prenylated forms of cyclo(L-Trp-L-Trp) are cytotoxic against human leukemia and ovarian cell lines.

msds of cyclo(Trp-Trp)