Biotin-Nobiletin

Biotin labeled Nobiletin/Nobiletin-Biotin is a functionalized derivative obtained by covalently labeling natural product naringin with biotin. Using a high affinity enrichment system of biotin streptavidin, the binding target protein of Chenpi peel extract was specifically captured from cell lysate. The specific targets and molecular mechanisms of Chenpi peel extracted anti heart failure, anti-inflammatory and other biological activities were analyzed through proteomic techniques.As a biotin labeled probe, it is used for in vitro Pull down experiments to directly verify the direct interaction between Chenpi extract and candidate target proteins, clarify the binding mode and affinity size of the two.

msds of Biotin-Nobiletin