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Alsterpaullone CAS No.237430-03-4
Alsterpaullone CAS No.237430-03-4
| Catalog # | Pkg Size | Price(USD) | Quantity | Buy this product |
|---|---|---|---|---|
| R-R-1399 | 5mg | 250.00 | + Add to cart |
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| R-R-1399 | 10mg | 400.00 | + Add to cart |
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Product description
Alsterpaullone (9-Nitropaullone)/CAS No.237430-03-4 is a potent CDK inhibitor, with IC50s of 35 nM, 15 nM, 200 nM and 40 nM for CDK1/cyclin B, CDK2/cyclin A, CDK2/cyclin E and CDK5/p35, respectively. Alsterpaullone also competes with ATP for binding to GSK-3alpha/GSK-3beta with IC50s of both 4 nM. Alsterpaullone has antitumor activity, and possesses potential for the study in neurodegenerative and proliferative disorders. Alsterpaullone induces apoptosis in leukemia cell line.
| Appearance | N/A |
|---|---|
| Molecular Weight | 293.28 |
| Purity | >90% |
| CAS | 237430-03-4 |
| Formula | C16H11N3O3 |
| Storage | -20℃, protected from light and moisture |
| Transportation | 4-25℃ temperature for up to 2 weeks |
| Stability | 1 year |
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