Acetal-PEG-NHS

Acetal-polyethylene glycol-NHS/Acetal-PEG-N-hydroxylsuccinimide. Acetal-PEG-NHS molecular chain is connected with Acetal at one end and sulfhydryl group at the other end, which is a linear heterobifunctional PEG derivative. It is used to cross link two amine-containing materials, such as protein to an AFM probe with amine group, so that two proteins and antibodies cross link, amine containing nanoparticles cross link to the enzyme. To crosslink a protein to an aminated surface, Acetal-PEG-NHS is reacted first with the surface, followed by acidic removal of acetal and regeneration of aldehyde, which is then reacted with the amine groups of proteins.

msds of Acetal-PEG-NHS