Ac-IEPD-AMC

Ac-IEPD-AMC,Ac-Ile-Glu-Pro-Asp-AMC(CAS :216757-33-4)is a fluorogenic substrate for caspase-8 and granzyme B. Caspase 8 is a cysteine protease involved in apoptosis induced by Fas and other stimuli. It is an attractive therapeutic target for a variety of degenerative disorders. Granzyme B is a serine protease found in cytotoxic T-cells and NK cells. It cleaves and activates a number of caspases involved in apoptosis.

MSDS of Ac-IEPD-AMC