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A-192621 CAS No.195529-54-5

A-192621 CAS No.195529-54-5

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R-R-1962 5mg 280.00
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R-R-1962 10mg 460.00
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Product description

A-192621/CAS No.195529-54-5 is a potent, nonpeptide, orally active and selective endothelin B (ETB) receptor antagonist with an IC50 of 4.5 nM and a Ki of 8.8 nM. The selectivity of A-192621 is 636-fold higher than ETA (IC50 of 4280 nM and Ki of 5600 nM). A-192621 promotes apoptosis in PASMCs. A-192621 alos causes elevation of arterial blood pressure and an elevation in the plasma ET-1 level.

A-192621 CAS No.195529-54-5

Appearance N/A
Molecular Weight 558.66
Purity >90%
CAS 195529-54-5
Formula C33H38N2O6
Storage -20℃, protected from light and moisture
Transportation 4-25℃ temperature for up to 2 weeks
Stability 1 year
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