(4E)-TCO-PEG4-DBCO

DBCO(dibenzocyclooctyne) is a kind of cycloalkyne.It can react with azide through strain promoted 1,3-dipolar cycloaddition in aqueous solution.This biorthogonal reaction is also called copper free click reaction.This reaction has excellent selectivity and biocompatibility, so complementary reagents can form covalent bonds with functional biological systems. Copper free click reaction has always been a powerful tool for catalyst free bioconjugation. Dbco reagent has fast affinity and stability in aqueous buffer,which can be used to label azide modified biomolecules with high specificity and reactivity.Trans cyclooctene (TCO),as a amphiphilic monomer,has been widely used in biological and material science research due to its advantages of no catalyst and fast reaction rate under physiological conditions.

msds----(4E)-TCO-PEG4-DBCO