4-(4-bromo-1H-pyrazol-1-yl)benzoic acid CAS No.:926212-84-2

4-(4-bromo-1H-pyrazol-1-yl)benzoic acid/CAS No.:926212-84-2 from ruixi. The synthesis of pyrazole derivatives, including those related to 4-(4-bromo-1H-pyrazol-1-yl)benzoic acid, involves multi-step reactions that include condensation, bromination, and nucleophilic addition processes. A notable example is the synthesis of 3-(2-(5-(benzylideneamino)-3-phenyl-1H-pyrazol-1-yl)thiazol-4-yl)-4-hydroxy-6-methyl-2H-pyran-2-one derivatives via a one-pot, four-component reaction. This method offers advantages such as ease of handling, good yields, and straightforward workup, indicating a trend towards more efficient synthesis routes for complex pyrazole derivatives.
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