[2,2-Bipyridine]-5-carboxylic acid CAS No.:1970-80-5

[2,2-Bipyridine]-5-carboxylic acid/CAS No.:1970-80-5 is a compound that has been synthesized and tested for various applications, including its role as an inhibitor of prolyl hydroxylase. The compound is part of a series of 2,2-bipyridines, which have been explored for their intriguing structure-activity relationships. The presence of a 5-carboxylate group is crucial for the inhibitory activity, as 2,2-bipyridines lacking this feature are poor inhibitors. This suggests the importance of net anionic charge, iron chelation, and potential binding modes at the catalytic subunit of the enzyme .
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