Product synthetic-chemistry-click-chemistry-dbco

Home > products > synthetic-chemistry> click-chemistry-dbco

Catalog	name	Description	price
R-M1-8983	6-Azide-Trehalose (6-TreAz)	6-Azide-Trehalose is a compound that is often used in chemical biology, bioconjugation, and glycobiology research.The azide group can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAC) or "click chemistry" with alkynes or other compounds containing terminal alkynes. This property makes 6-Azide-Trehalose valuable in bioorthogonal labeling and functionalization of biomolecules, as well as in metabolic labeling and imaging studies. The trehalose backbone also provides stability and protection to the azide group, allowing for specific targeting and conjugation without compromising the functional group.	price>
R-M1-9043	endo-BCN-NHS carbonate,cas1426827-79-3	endo-BCN-NHS carbonate is a chemical compound used in bioconjugation and bioorthogonal chemistry. The compound contains an endo-BCN (bicyclo[6.1.0]non-4-ene) group, an NHS (N-hydroxysuccinimide) ester, and a carbonate functional group. The endo-BCN group can participate in copper-free click chemistry reactions with tetrazine-functionalized molecules, allowing for specific and selective labeling or modification of biomolecules. The NHS ester provides a means for coupling the compound to primary amines, such as those present in proteins or nucleic acids, and the carbonate functional group may contribute to the stability and reactivity of the compound.	price>
R-M1by-9084	2-3-cGAMP-DBCO conjugate	2-3-cGAMP-DBCO conjugate conjugate is an excellent component for developing 2-3-cGAMP probes for studying their biological activity and function.2-3-cGAMPhas been shown to activate the immune system and enhance the efficacy of immune checkpoint inhibitors, making it a cancer immunotherapy.	price>
R-M1by-9085	2,3-cGAMP-azide	2,3-cGAMP-azides are excellent reagents for coupling 2,3-cGAMP to alkyne modified biological targets such as proteins, peptides, and nucleic acids.In recent years, 2,3-cGAMP has attracted much attention as a potential target for treating diseases such as cancer and viral infections. Research has shown that immune checkpoint inhibitors are a cancer immunotherapy that can activate the immune system and enhance its efficacy. 2,3-cGAMP (cyclic GMP AMP) is a cyclic dinucleotide second messenger molecule that plays a crucial role in the innate immune system. It is synthesized by cGAS (cyclic GMP AMP synthase) in response to cytoplasmic DNA released by damaged or infected cells. Once synthesized, 2,3-cGAMP binds to the adapter protein STING (a stimulatory factor of the interferon gene) and triggers downstream signaling pathways, producing type I interferon and other cytokines, thereby generating an immune response against invading pathogens.	price>
R-M1-9154	DBCO-SS-AAKLVFFWHRSYYTWNLNT	DBCO-SS-AAKLVFFWHRSYYTWNLNT is commonly used in studies involving chemical biology, drug delivery, or bioconjugation, typically for linking specific molecules or groups to the peptide for various biological or chemical applications.	price>
R-M2-9299	Heparin-DBCO	Heparin-DBCO is typically designed for biomedical applications, particularly in drug delivery systems and biomarkers (to achieve specific cell targeting).	price>
R-M2-9300	Heparin-PEG4-DBCO	Heparin-PEG4-DBCO is likely utilized in developing novel drug delivery systems, molecules with specific biological activities, or for applications involving targeted peptides and more.	price>
R-M2-9343	DBCO-Alginate	DBCO-sodium alginate refers to a specific bioconjugation system where DBCO (Dibenzocyclooctyne) is conjugated to sodium alginate. This combination allows for the functionalization of sodium alginate with DBCO groups, enabling subsequent conjugation with azide-functionalized molecules via copper-free click chemistry. By linking DBCO to sodium alginate, researchers can create a platform for bioconjugation applications in various fields such as drug delivery, tissue engineering, and diagnostics, leveraging the specificity and efficiency offered by click chemistry reactions.	price>
R-M2-9365	NHS-PEG2k-TK-DBCO	NHS-PEG2k-TK-DBCO serves as a flexible tool in bioconjugation strategies for attaching molecules in a controlled and specific manner, often applied in areas like drug delivery, imaging, and diagnostics in biomedical research.	price>
R-M2-9396	DBCO-TK-MAL	DBCO-TK-MAL/Dibenzocyclooctyne-thioketal-maleimide is a multi-component molecule that comprises a cycloalkyne, a butyrate salt, and a maleimide group. This compound may be used to deliver bioactive molecules, drug payloads, or imaging dyes to specific biological targets with high specificity and low off-target effects.	price>

...