Product synthetic-chemistry-click-chemistry-dbco

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Catalog	name	Description	price
R-R-0076	Azido-PEG8-Br	Azido-PEG8-Br is a bifunctional PEG linker with a bromide (Br) group and an azide (N3) group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The bromide (Br) is a good leaving group for nucleophilic substitution reactions.	price>
R-R-0140	DBCO-PEG1-amine TFA salt cas:2364591-79-5	DBCO-PEG1-amine/DBCO-PEG1-amine TFA salt/cas:2364591-79-5/Dibenzocyclooctyne-polyethylene glycol1-amine is widely applied in pharmaceutical research and development for creating targeted drug delivery systems, bioimaging probes, and biomolecular conjugates. Its copper-free click chemistry property enables efficient bioorthogonal coupling, minimizing toxicity and interference in biological systems. This linker is particularly valuable for designing antibody-drug conjugates (ADCs), enhancing solubility and pharmacokinetics of therapeutic agents, and facilitating precise molecular interactions for improved therapeutic efficacy.	price>
R-R-0440	DBCO-(PEG2-Val-Cit-PAB)2	DBCO-(PEG2-Val-Cit-PAB)2 is a dual cleavable ADC linker for antibody-drug conjugates (ADCs). DBCO-(PEG2-Val-Cit-PAB)2 is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.	price>
R-R-0442	DBCO-PEG3 acetic-EVCit-PAB	DBCO-PEG4 acetic-EVCit-PAB CAS:2253947-17-8 is a chemical compound used in bioconjugation and drug delivery research. It is a derivative of dibenzocyclooctyne (DBCO), a reactive group that can be selectively and efficiently conjugated to azides or other strained alkenes. DBCO-PEG4 acetic-EVCit-PAB contains a PEG spacer consisting of four ethylene glycol units, a maleimide group, and a p-aminobenzoic acid group (PAB), which can be used to attach the compound to proteins or peptides through the formation of stable thioether bonds. This compound is a valuable tool for the development of targeted drug delivery systems or bioconjugates for imaging, diagnosis, or therapeutic applications.	price>
R-R-0444	DBCO-PEG3-propionic-Val-Cit-PAB	DBCO-PEG3-propionic-Val-Cit-PAB-OH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADC). The Val-Cit is specifically cleaved by cathepsin B. As this enzyme is only present in the lysosome the ADC payload will be release only in the cell. The Boc group can be deprotected under acidic conditions to generate a free amine group.	price>
R-R-0445	DBCO-PEG4-propionic EVCit-PAB	DBCO-PEG4-propionic EVCit-PAB is a chemical compound used in bioconjugation and drug delivery applications. It is a derivative of propionic acid, a small molecule that contains a linker consisting of four ethylene glycol units and a strained alkyne group, known as dibenzocyclooctyne (DBCO). The compound can be used to specifically and efficiently attach to molecules containing azide groups, providing a platform for drug delivery, imaging, or other applications.	price>
R-R-0449	DBCO-PEG4-acetic-Val-Cit-PAB	DBCO-PEG4-acetic-Val-Cit-PAB is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).	price>
R-R-0458	DBCO-PEG3-oxyamine	DBCO-PEG3-oxyamine is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).	price>
R-CD-045	DBCO-COOH/acid,CAS: 1353016-70-2	DBCO-acid,Dibenzocyclooctyne-acid from ruixi.Dibenzocyclooctyne (dbco) was used in the azido alkyne cycloaddition (spaac) reaction without copper ion catalysis. The kinetic constant of the second order reaction was 1.Dbco series products include dbco acid,dbco amine,dbco peg COOH,dbco peg amine, as well as dbco labeled biotin,fluorescent dyes and biochemical small molecules.	price>
R-CD-050	DBCO-NHS ester	DBCO-NHS ester,DBCO-N-hydroxylsuccinimide ester from ruixi.Dbco (dibenzocyclooctyne) is a kind of cycloalkyne.It can react with azide through strain promoted 1,3-dipolar cycloaddition in aqueous solution.This biorthogonal reaction is also called copper free click reaction.This reaction has excellent selectivity and biocompatibility,so complementary reagents can form covalent bonds with functional biological systems.Copper free click reaction has always been a powerful tool for catalyst free bioconjugation.Dbco reagent has fast affinity and stability in aqueous buffer,which can be used to label azide modified biomolecules with high specificity and reactivity. Active esters modify molecules with primary amines.	price>

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