Product synthetic-chemistry-protac-linker

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Catalog	name	Description	price
R-M2-9907	QMGFMTSPKHSV-(C Terminal-Ahx-Val-Cit-PABC-MMAE)	QMGFMTSPKHSV-(C Terminal-Ahx-Val-Cit-PABC-MMAE) is a targeted peptide–drug conjugate (PDC) designed for site-specific delivery of a cytotoxic payload. QMGFMTSPKHSV: a targeting peptide that binds selectively to specific cellular receptors or tumor-associated markers, guiding the conjugate to diseased tissues. Peptide QMGFMTSPKHSV: N-terminal amino group, k-terminal amino group, and histidine amino group all need to be protected. Ahx (6-aminohexanoic acid): acts as a flexible spacer, improving the accessibility and stability of the linkage between the peptide and the cleavable linker. Applications: Used as a peptide–drug conjugate for targeted cancer therapy, where the peptide enables selective tumor targeting and the Val-Cit-PABC-MMAE module ensures controlled intracellular drug release after enzymatic activation, minimizing systemic toxicity.	price>
R-M1-8361	NHS-PEG4-Fmoc HYNIC	NHS-PEG4-Fmoc HYNIC is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).	price>
R-M1-8618	DOTA-PEG4-DBCO	DOTA-PEG(4)-DBCO/DOTA-PEG4-dibenzocyclooctyne/DOTA-PEG4-DBCO(dibenzocyclooctyne)/DBCO-PEG4-DOTA is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.	price>
R-M1-8623	FMOC-SS-COOH	FMOC-SS-COOH represents a molecule with an FMOC protecting group, a disulfide bond, and a carboxylic acid group. This compound is often used in peptide synthesis or other organic chemistry applications where the disulfide bond plays a role in cross-linking or modification of molecules. The FMOC group acts as a protecting group that can be removed later in the synthesis process.	price>

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