Catalog name Description price
R-C-3267 GANT61 CAS:500579-04-4 GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription,inhibits hedgehog with IC50 of 5μM,displays selectivity over other pathways,such as TNF and glucocorticoid receptor gene transactivation.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-C-3269 ETC-159 CAS:1638250-96-0 ETC-159 is a potent and specific inhibitor of Wnt secretion.ETC-159 inhibits beta-catenin reporter activity in a dose-dependent manner with an IC50 of 2.9nM.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-C-3271 CCT251545 CAS:1661839-45-7 CCT251545 is an orally bioavailable and potent inhibitor of WNT signaling with an IC50 of 5 nM in 7dF3 cells.CCT251545 is a selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-C-3364 JW74 CAS:863405-60-1 JW74 is an efficient and specific inhibitor of the canonical Wnt signaling. JW74 shows a reduction of canonical Wnt signaling in the ST-Luc assay with IC50 values of 790 nM.The product is only suitable for scientific research and test, not for clinical experiment and human body. price>
R-C-3365 ICG-001 CAS:780757-88-2 ICG-001 is a specific inhibitor of Wnt/β-catenin signaling pathway that inhibits β-catenin/cyclic AMP response element-binding (CREB) protein transcription (IC50=3 microM) .Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-C-3366 IWP-2 CAS:686770-61-6 IWP-2 is an inactivator of Porcn function and inhibitor of Wnt production,and blocks beta-catenin accumulation.Wnt/b-catenin (canonical) pathway maintains transcriptional programs that enable stem cells to remain multipotent.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-C-3367 KYA1797K CAS:1956356-56-1 KYA1797K is a highly potent and selective Wnt/beta-catenin inhibitor with IC50 of 0.75 μM (TOPflash assay).Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-C-3368 Longdaysin CAS:1353867-91-0 Longdaysin is a inhibitor of the Wnt/β-catenin signaling pathway, which exerts antitumor effect through blocking CK1δ/ε-dependent Wnt signaling.Longdaysin inhibits CK1α,CK1δ,CDK7,and ERK2 with IC50s of  5.6µM,8.µM,29µM,and 52µM, respectively.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-C-3369 WAY-316606 CAS:915759-45-4 WAY 316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. The affinity of WAY-316606 for sFRP-1 is determined using the FP binding assay with IC50 of 0.5 μM.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>
R-C-3371 PF 670462 CAS:950912-80-8 Potent and selective casein kinase 1ε (CK1ε)and CK1δ inhibitor(IC50 values are 7.7 and 14nM respectively)that displays>30-fold selectivity over 42 other common kinases. Inhibits PER protein nuclear translocation(EC50=290nM)causing phase shifts in circadian rhythms and attenuates methamphetamine-stimulated locomotion in vivo.Our products are only suitable for scientific research experiments, not for clinical experiments and human body. price>