Product synthetic-chemistry-protein-crosslinkers

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Catalog	name	Description	price
R-M1-8128	DOX-GA	DOX-GA,Doxorubicin-Glycyrrhetinic acid modified recombinant human serum albumin nanoparticles for targeting liver tumor chemotherapy. Doxorubicin-Glycyrrhetinic acid is an efficient nanoplatform for targeting drug delivery system for liver cancer.	price>
R-M1-8132	OVA-BIOTIN	OVA-BIOTIN,Ovalbumin-BIOTIN from kamulin. BIOTIN modified ovalbumin.Ovalbumin(OVA)is the main protein found in egg white,accounting for about 55% of the total protein.	price>
R-M1-8141	Rat tail tendon collagen I type	Rat tail tendon collagen type can be used to coat cell culture vessels to cultivate some cells that are not easy to adhere to the wall in ordinary cell culture vessels. It can also be used to prepare three-dimensional gels to simulate a real growth environment and allow cells to grow in a three-dimensional environment.	price>
R-M2-9813	E2s protein-(Mal-PEG1-Val-Cit-PABC-OH)-artesunate	E2s protein-(Mal-PEG1-Val-Cit-PABC-OH)-artesunate is a protein–drug conjugate (PDC) or bioconjugate, constructed for targeted or controlled drug delivery. Applications: Targeted protein-drug conjugate therapy for cancer or other diseases with cathepsin B overexpression. Controlled-release drug delivery with enzyme-triggered activation. Potential theranostic conjugate if E2s is also functionalized for imaging or targeting	price>
R-M2-9814	Artesunate-E2s protein(148 amino acids)	Artesunate-E2s protein(148 amino acids) is a protein-drug conjugate (PDC) composed.Ubiquitin-conjugating enzymes (E2s)/E2s Protein (148 amino acids) : refers to proteins in the E2 family.A medium-sized protein (~16–18 kDa, depending on sequence) that serves as a carrier or targeting moiety. Its function can range from tumor targeting to carrier-mediated delivery, depending on the intrinsic properties of protein. Applications: Targeted cancer therapy: Artesunate has demonstrated anticancer potential via oxidative stress pathways. Protein-based drug delivery: Enhances solubility, stability, and pharmacokinetics of artesunate. Potential theranostic systems if E2s is further functionalized with imaging or targeting motifs.	price>
R-M2-9829	FAPI-2286	FAPI-2286/FAP-2286/CasNo:2581741-18-4 is a potent and selective FAP-binding peptide coupled to a radionuclide chelator with a mean IC50 value of 2.7 nM for binding to FAP. FAP-2286 consists of two functional elements: a FAP-targeting peptide and a chelator used to attach radioisotopes. FAP-2286 and its metal complexes demonstrated high affinity to FAP recombinant protein and cell surface FAP expressed on fibroblasts. Biodistribution studies in mice showed rapid and persistent uptake of 68Ga-FAP-2286, 111In-FAP-2286, and 177Lu-FAP-2286 in FAP-positive tumors, with renal clearance and minimal uptake in normal tissues. 177Lu-FAP-2286 exhibited antitumor activity in FAP-expressing HEK293 tumors and sarcoma patient-derived xenografts, with no significant weight loss. In addition, FAP-2286 maintained longer tumor retention and suppression in comparison to FAPI-46.	price>
R-M1-8196	PTX-SS-NHS	PTX-SS-NHS is a cleavable ADC linker,which can be used to synthesize antibody coupled drugs (ADC).	price>
R-M1-8252	SH-lactoferrin	SH-lactoferrin,Thiol-lactoferrin from kamulin.	price>
R-M1-8260	RSA(dimer modified)	Rabbit Serum Albumin, the albumin in the blood mainly plays the role of maintaining osmotic pressure, PH buffer, carrier and nutrition. In serum-free animal cell culture, the addition of albumin can play a physiological and mechanical protective role as a carrier. Compared to bovine serum albumin, rabbit serum albumin has a lower blood background due to factors such as shorter growth cycles and easier control of breeding conditions in rabbits. The application of rabbit serum albumin as a sealing agent for diagnostic reagents can effectively reduce the background of the reagents.	price>
R-M1-8274	Concanavalin A-sepharose	Concanavalin A is a tetrameric protein,the minimal structure exhibiting high affinity binding of carbohydrates is the dimeric form. The dimer form of ConA is an active stable structure, and the tetramer-dimer transition can be promoted by low pH or succinylation of the protein.Concanavalin A (Con A) is a plant lectin that is purified from jack beans. Con A binds to the mannose residues of various glycoproteins and activates lymphocytes.	price>

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