Product apis-dna-damage-dna-repa

Home > products > apis> dna-damage-dna-repa

Catalog	name	Description	price
R-C-433	ABT-888	ABT-888 is an effective inhibitor of PARP.It has good oral bioavailability,can cross the blood-brain barrier,and can enhance temozolomide,platinum, cyclophosphamide and radiation.This broad spectrum of chemical and radioenhancement makes this compound an attractive candidate for clinical evaluation.	price>
R-C-446	Marbofloxacin	Marbofloxacin is a potent antibiotic inhibiting bacterial DNA replication.	price>
R-C-447	Moxifloxacin	Moxifloxacin(BAY12-8039)is a fourth-generation synthetic fluoroquinolone antibacterial agent.Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis,acute bacterial exacerbations of chronic bronchitis,and community-acquired pneumonia.	price>
R-C-449	Rucaparib (AG-014699) phosphate cas:459868-92-9	Rucaparib(AG-014699,PF-01367338)is an inhibitor of PARP with Ki of 1.4 nM for PARP1 in a cell-free assay,also showing binding affinity to eight other PARP domains.	price>
R-C-501	KU55933 cas:587871-26-9	KU-55933 (ATM Kinase Inhibitor) is a potent and specific ATM inhibitor with IC50/Ki of 12.9 nM/2.2 nM in cell-free assays,and is highly selective for ATM as compared to DNA-PK,PI3K/PI4K,ATR and mTOR.KU55933 (ATM Kinase Inhibitor) inhibits the activation of autophagy initiating kinase ULK1 and results in a significant decrease of autophagy.	price>
R-C-512	Pyroxamide cas:382180-17-8	Pyroxamide is a potent inhibitor of histone deacetylase 1(HDAC1) with an ID50 of 100 nM.Pyroxamide can in duce apoptosis and cell cycle arrest in leukemia.	price>
R-C-513	CP466722 cas：1080622-86-1	CP-466722 is a rapidly reversible inhibitor of ATM,with an IC50 of 4.1 μM,and has no effects on PI3K or closely related PI3K-like protein kinase (PIKK) family members.	price>
R-C-518	HQL-79 cas:162641-16-9	HQL-79 is a selective inhibitor of hematopoietic prostaglandin D (PGD) synthase, that structurally is a synthetic tetrazole compound originally prepared as a possible antihistamine.	price>
R-C-565	ACY-1215 cas:1316214-52-4	Ricolinostat (ACY-1215,Rocilinostat)is a selective HDAC6 inhibitor with IC50 of 5 nM in a cell-free assay.It is>10-fold more selective for HDAC6 than HDAC1/2/3(class I HDACs)with slight activity against HDAC8,minimal activity against HDAC4/5/7/9/11,Sirtuin1,and Sirtuin2.Ricolinostat (ACY-1215)suppresses cell proliferation and promotes apoptosis.	price>
R-C-587	Amrubicin cas:110267-81-7	Amrubicin is a synthetic anthracycline antibiotic.It inhibits DNA topoisomerase II. Antineoplastic.	price>

...