Catalog name Description price
R-M-188 Protein Kinase C(PKC) [19-35] Peptide  This peptide corresponds to the residues 19-35 of the pseudosubstrate domain of protein kinase C isoforms alpha and beta. The peptide is a potent inhibitor of both the phosphorylation of protein kinase C substrates (Ki = 147 nM) and the autophosphorylation of protein kinase C whereas it has a low inhibitory activity on protein kinase A (IC50 = 423 mM). price>
R-M-189 PKA Inhibitor [6-22] Peptide  PKA Inhibitor [6-22] Peptide ,protein kinase A Inhibitor [6-22] Peptide from ruixi.This peptide is a potent and competitive inhibitor of protein kinase A (PKA) with a Ki = 1.7 nM. The peptide sequence corresponds to residues 6-22 of human cAMP-dependent protein kinase inhibitor alpha (PKI-alpha) and is amidated at the C-terminus end. PKI-alpha interacts with the catalytic subunit of PKA after the cAMP-induced dissociation of its regulatory chains. price>
R-M-190 Peptide P60 Peptide P60 (FOXP3 inhibitor P60) is a 15-mer synthetic peptide, cell-permeable inhibitor of FOXP3, binds specifically to FOXP3.Peptide P60 has demonstrated potential of inhibiting the immunosuppressive activity of murine and human derived regulatory T-cells (Tregs) and enhances the effector T-cell stimulation in vitro by binding to regulatory T-cells specific forkhead/winged helix transcription factor 3 (FOXP3). Peptide P60 can enter the cells to inhibit FOXP3 nuclear translocation and activity on other transcription factors. In vitro, peptide P60 (100 uM) inhibited murine and human-derived Treg and improved effector T cell stimulation. price>
R-M-191 Octreotide Acetate Peptide Octreotide Acetate is an octapeptide analogue of somatostatin.Octreotide Acetate Peptide is a very potent inhibitor of many hormones such as growth hormone, glucagon and insulin. Octreotide acetate Peptide mimics the effects of natural hormone somatostatin. Octreotide acetate is the water-soluble acetate salt of a cyclic octapeptide. It is used in the treatment of diarrhea associated with carcinoid tumors, and profuse watery diarrhea associated with vasoactive intestinal peptide tumors (VIPoma). It is also a treatment for acromegaly. price>
R-M-192 Kallikrein Inhibitor Peptide Kallikreins (tissue and plasma kallikreins) are serine proteases that liberate kinins (bradykinin and kallidin) from the kininogens, which are plasma proteins that are converted into vasoactive peptides. The Kallikrein Inhibitor Peptide corresponds to aa386-391 of bovine kininogen-1 that encompasses the aa388-389 kallikrein proteolytic site. The synthetic kallikrein inhibitor can attenuate breast cancer cell invasion, therefore it is investigated for its role in invasion and metastasis of cancer cells. price>
R-M-193 Fibronectin CS-1 Peptide Fibronectin CS-1 Peptide,Fibronectin connecting segment 1 Peptide from ruixi.The fibronectin connecting segment 1 (CS-1) peptide corresponds to the cell attachment domain in the type-III homology connecting strand (IIICS) of fibronectin (aa 2009-2016 in human fibronectin). Fibronectin CS-1 peptide inhibits tumor metastasis in spontaneous and experimental models. price>
R-M-194 cGKI Kinase Inhibitor Peptide The peptide is a synthetic inhibitor of the cGKI protein kinase. The sequence corresponds to the mutated S32A phosphorylation site analog within residues 29-35 of human histone H2B. The cGKI kinase belongs to the AGC Ser/Thr family, cGMP subfamily, and has two isoforms, alpha and beta, that become active upon homodimerization and cGMP binding. price>
R-M-155 Tyr-Specific Protein Kinase Inhibitor Peptide This peptide is an inhibitor for tyrosine protein kinases such as EGFR and Src subfamily members (IC50=7.5 mM for pp60 v-src).The sequence corresponds to residues 140-160 of the proto-oncogene tyrosine protein kinase Src (c-Src). price>
R-M-484 Ac-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Ile-Glu-Thr-Asp-aldehyde trifluor Acetyl-AAVALLPAVLLALLAP-IETD-CHO, the potent reversible caspase-8 inhibitor IETD-CHO is rendered cell-permeable by attaching a non-polar CPP corresponding to the Kaposi fibroblast growth factor (FGF) signal peptide sequence. price>
R-M-286 Caloxin 2A1 trifluoroacetate salt Caloxin 2A1(CAS :350670-85-8) is a selective extracellular inhibitor of the plasma membrane Ca²⁺-pump. price>