MAZ51 CAS:163655-37-6

MAZ51 is a potent and selective inhibitor of vascular endothelial growth factor receptor(VEGFR)-3(Flt-4)tyrosine kinase.MAZ51 induces cell rounding and G2/M cell cycle arrest in glioma cells through phosphorylation of Akt/GSK3β and activation of RhoA.MAZ51 inhibits the proliferation and induces the apoptosis of a variety of non-VEGFR-3-expressing tumor cell lines.

msds---MAZ51