GDC0623 CAS:1168091-68-6

GDC-0623(G-868)is an orally active,selective MEK inhibitor with potential antineoplastic activity.MEK inhibitor GDC-0623 specifically inhibits mitogen-activated protein kinase kinase(MEK or MAP/ERK kinase),resulting in inhibition of growth factor-mediated cell signaling and tumor cell proliferation.MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that regulates cell growth;constitutive activation of this pathway has been implicated in many cancers.Check for active clinical trials or closed clinical trials using this agent.

msds---GDC0623